History of Company
Born in Senigallia in 1868, Alessandro Bruschettini was one of the best known scientist of the period. In 1890, at the age of 22, he graduated in medicine in Bologna with an original thesis based on the rabies virus and he gained the prestigious award for scientific merit Vittorio Emanuele a year later. In 1892, just 2 years after graduation, he proved together with Chantemesse and Widal , that it was possible to get a solid immunity against typhoid with crops of responsible bacilli killed by heat at 60 ° C. During the same year, as a consequence of a flu epidemic in Bologna, he was able to isolate a pathogen like the one described by Pfeiffer in the blood of patients. This raised scientific discussions at international level which reaffirmed the great intellectual acuteness of the young researcher. In 1894 he was in London in the laboratory of Professor Horsley at University College. At the end of 1894 he was back in Bologna with Professor Tizzoni and in 1895 he attended at the University of Turin. He obtained a teaching qualification in Hygiene and he directed the section of the bacteriological laboratory of Parasitology until 1904. In 1899 he described the amazing results obtained in the treatment of tuberculosis with a serum-vaccine which acting directly in the fabric tuberculous allowed to locally limit the progression of the disease till the moment it extinguished the early outbreak. Then he was in contact with Koch’s school in Germany and was estimated supervisor of several scientific papers in Italy and abroad, in which he described his serum-vaccine. He also reported on the improvements made to its new Health vaccines and on the need to resort to active immunization by not altered and unmodified in their biological characteristics germs.
He also drew scholars attention on the importance of cellular toxins released at tissue death and on the opportunity to fight microbial infections incurred by using polyvalent vaccines. In 1905 he left Turin and finally arrived in Genoa where he worked at the Universty’s Institute for Infectious Diseases until 1912.
In Genoa he realized his dream: the Laboratory of Experimental Therapy, where he mainly devoted himself to the study of tuberculosis and to the realisation of a series of Health vaccines. They were successful both in the human and the in veterinary field for their original method of preparation, for the therapeutic effectiveness and the simlple use, especially in respect of the “Wright” vaccines. After the first World War he was in France where he belonged to several prestigious institutions of the time and where he started local production of some of his vaccines. He may be considered a modern scientist for many reasons. He used his international contacts for his cultural growth, he tried to get a constructive dialogue with the other researchers through the results publication and the research presentation at conferences. Finally he created a company which proved his discoveries quality from a commercial point of view starting from the results of his basic research. In addition he was a really cultured person.
Intellectual, researcher and businessman, he was able to develop drugs which used the interface between innate immunity and adaptive immunity to carry out their function in a way. It’s important to remember that this interface has been under study only for few years and that today it’s one of the frontiers of the new treatments in the infectious diseases.. He had both Marches and Ligurian distinctive features. Austere, determined man and hard worker, he had a complete view of life.He was a man learned in many branches of knowledge: classical subjects, European literature, music. He was also a careful bibliophile but his great passion was European history, which he knew very well thanks to the excellent knowledge of the major European languages that allowed him to access to the best historical literature of his time.
It’s important to remember that his travels in Italy and abroad, its continuous contacts with the main centers of medical and scientific research never stopped until his death in 1932. In fact Alessandro Bruschettini personally prepared his new curative vaccines using its original and innovative method till the end of his life.
The next generations continued the founder’s path, at first enlarging the company in 1937 and then beginning to initiate the study, the development and the production of new specialities , in other therapeutic areas too.
In the Sixties of the Twentieth Century, the company decided to enter the ophthalmic industry with innovative products that have been developed from a pharmacological and clinical point of view to the final production and marketing. So now we have the fourth generation of a scholars and entrepreneurs family who crossed a difficult century to deliver a solid Italian industrial reality whose products are appreciated both in our country and at international level.